Netherlands, Argentina, France and England have already booked their spots in the World Cup quarter-finals — but four last-16 matches are still to come.
On Monday, surprise package Japan take on Croatia and favourites Brazil meet South Korea.
Group G winners Morocco come up against Spain on Tuesday and the round concludes later that day when Cristiano Ronaldo will look to inspire Portugal to victory over Switzerland.
Qatar 2022 World Cup round of 16 fixtures
The knockout phase got under way with Netherlands cruising to a 3-1 victory over the United States.
Louis van Gaal's men will face Argentina in the last eight after Lionel Messi inspired the South Americans to a 2-1 win over Australia.
Olivier Groud became France's all-time top scorer as they overcame Poland, while England brushed aside Senegal 3-0 following some hairy moments in the first half to set up a clash with Les Bleus.
Check out the key information for all the last-16 fixtures below.
Saturday, December 3
Netherlands 3-1 United States (Khalifa International Stadium, Al Rayyan)
Argentina 2-1 Australia (Ahmad bin Ali Stadium, Al Rayyan)
Sunday, December 4
France 3-1 Poland (Al Thumama Stadium, Doha)
England 3-0 Senegal (Al Bayt Stadium, Al Khor)
Monday, December 5
Japan vs Croatia (Al Janoub Stadium, Al Wakrah, 3pm, BBC One)
Brazil vs South Korea (Stadium 974, Doha, 7pm, ITV1)
Tuesday, December 6
Morocco vs Spain (Education City Stadium, Al Rayyan, 3pm, ITV1)
Portugal vs Switzerland (Lusail Iconic Stadium, Lusail, 7pm, ITV1)
Quarter-finals: Friday, December 9 and Saturday, December 10
Semi-finals: Tuesday, December 13 and Wednesday, December 14
Third-place play-off: Saturday, December 17
Final: Sunday, December 18
All kick-off times are GMT.
