Khvicha Kvaratskhelia and Victor Osimhen ruthlessly punished three defensive errors as Napoli beat Spezia 3-0 to increase their lead at the Serie A summit to 16 points.
Luciano Spalletti's side may not have been at their swashbuckling best but produced a professional display at Stadio Alberto Picco on Sunday and never looked at risk of dropping points once they edged in front.
Marco Asensio saw his penalty saved as Nacho's own goal condemned Real Madrid to a surprise 1-0 defeat against mid-table Mallorca in LaLiga on Sunday.
Madrid fell behind when stand-in captain Nacho deflected Vedat Muqiri's header beyond Andriy Lunin — a late replacement for the injured Thibaut Courtois — 13 minutes in.
Napoli coach Luciano Spalletti is plotting an offensive on two fronts in the final months of the season as he hopes to win Serie A and the Champions League.
Spalletti's side were comfortable 3-0 winners away to Spezia on Sunday, briefly increasing their lead at the summit to 16 points.
Carlo Ancelotti defended Vinicius Junior after the Brazil forward was subjected to rough treatment during Real Madrid's defeat at Real Mallorca.
Los Blancos missed the chance to close the five-point gap on LaLiga leaders Barcelona after Nacho's own goal condemned them to a 1-0 loss on Sunday, in which Marco Asensio also saw a penalty saved.
David de Gea is confident his ongoing contract talks with Manchester United will end "in a good way".
De Gea has been an ever-present between the sticks for United this season, with Newcastle United's Nick Pope (12) the only goalkeeper to top his tally of eight Premier League clean sheets.
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