Diego Alonso blamed Uruguay's World Cup exit on Portugal's last-gasp penalty in their second Group H game.
La Celeste looked on course to reach the knockout stage on Friday with a 2-0 win over Ghana, yet South Korea's late winner against Portugal saw them progress at Uruguay's expense.
Luis Suarez claimed FIFA "is always against Uruguay" as his World Cup career ended in tears and a group-stage exit in Qatar.
The former Barcelona, Liverpool and Atletico Madrid striker played in Friday's 2-0 win against Ghana, which came thanks to a double from Giorgian de Arrascaeta.
Uruguay head coach Diego Alonso believes his Real Madrid star Federico Valverde is best suited as a defensive midfielder, but that the team will need to perform better as a whole to allow him to "shine more".
Alonso's comments came after Monday's disappointing 2-0 loss to Portugal, leaving Uruguay alongside Mexico and Tunisia as the only teams without a goal through two matches.
Bruno Fernandes scored both goals as Portugal secured a World Cup last-16 place with a 2-0 win over Uruguay at Lusail Stadium.
The Manchester United midfielder broke the deadlock in a scrappy Group H clash when his 54th-minute cross, which was aimed at Cristiano Ronaldo, nestled in the far corner.
Ghana head coach Otto Addo insists the Black Stars will not "seek revenge" against Uruguay when they collide in a repeat of their infamous 2010 World Cup quarter-final.
Following their narrow 3-2 win over South Korea on Monday, Addo's side will seal their last-16 place with victory over La Celeste in their final Group H match on Friday.
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